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Introduction:Human Chorionic Gonadotropin (HCG) is a peptide hormone produced in
pregnancy, which is made by the embryosoon after conception and
later by the syncytiotrophoblast (part of the placenta). Its role
is to prevent the disintegration of the corpus luteum of the ovary
and thereby maintain progesterone production that is critical for a
pregnancy in humans. HCG may have additional functions, for
instance it is thought that it affects the immune tolerance of the
pregnancy. Early pregnancy testing generally is based on the
detection or measurement of HCG.
Description:Human Chorionic Gonadotropin is produced from a sterile preparation
of placental glucoprotein urine of pregnant women having a total
molecular mass of 36,700 Dalton. The HCG (purified by proprietary
chromatographic techniques) consists of 237 amino acids, chain-92
amino acids and b chain-145 amino acids.
Greater than 98% as determined by:
(a) Analysis by HPLC.
(b) Analysis by SDS-PAGE.