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Introduction:PT-141 is a compound under drug development by Palatin Technologies
as a treatment for hemorrhagic shock and reperfusion injury. It
functions by activating the melanocortin receptors MC1R and MC4R,
to modulate inflammation and limiting ischemia.It was originally
developed for use in treating sexual dysfunction but this
application was temporarily discontinued in 2008, after concerns
were raised over adverse side effects of increased blood pressure.
Currently, Palatin is in negotiations with the FDA to resume Human
Phase 2 studies using a new subcutaneous drug delivery system that
appears to have little effect on blood pressure.
Description:PT-141 has 191 amino acid residues and a molecular weight of 22,125
Greater than 98% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
1. For children due to endogenous growth hormone deficiency caused
2. Reduce excess body fat, increase muscle mass and bone density,
and reduce wrinkling of the skin, strengthen the immun system.